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Heat transfer fluids – Pharmaceutical Manufacturing Applications

Therminol liquid phase heat transfer fluids have been used for many years by the pharmaceutical industry. Precise temperature control is important for these multi-step chemical processes that may span temperatures ranging from -125°C (-195°F) to 350°C (400°F). Pharmaceutical manufacturers prefer to use a single fluid with excellent heat transfer properties over a wide temperature range that will perform well at these extreme operating conditions.

Therminol D-12 liquid phase heat transfer fluid is well suited for applications requiring efficient cooling and heating between -45 °C and 230 °C (-50 °F and 450 °F). This wide temperature use range is preferred for most pharmaceutical applications and can eliminate the need for multiple fluids to be used at different operating conditions. Using Therminol D-12 as a single fluid in a cooling/heating system can simplify heat transfer system design and minimize operational problems. Therminol D-12 is practically non-toxic and has almost no odor.

Therminol VLT liquid phase heat transfer fluid is ideal for applications requiring extremely low temperature cooling with flexible heating capabilities. The wide operating range of -115 °C (-175 °F) to 175 °C (350 °F) allows a single fluid to be used for general purpose pharmaceutical processing and very low temperature chiral chemistry where a high degree of reaction selectivity is required.

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